Comparative Evaluation of Physical, Chemical and Biological methods of Nanoparticle Synthesis: A review

*Correspondence to: Mekuanint Lewoyehu, Department of Chemistry, College of Science, Bahir Dar University , Ethiopia
Received: Apr 02, 2021; Accepted: May 13, 2021; Published: May 17, 2021
Citation: Mekuanint Lewoyehu (2021) Comparative Evaluation of Physical, Chemical and Biological methods of Nanoparticle Synthesis: A review. J Nanomed Nanotech Nanomat 2:109.
Copyright: ©2021 Lewoyehu M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Recently, Nanomaterials and Nanotechnologies attract the interest of many researchers. This is due to the application of this technology in many disciplines such as Engineering, Medicine, Computer science, Material Science, Biology, Chemistry, physics and Agriculture. Thus, scientists and engineers are doing researches and have made significant improvements in the synthesis methods of nanomaterials. However, most of the currently available techniques are conventional physical and chemical methods which are expensive, labor-intensive, potentially harmful to the environment and living organisms, and inefficient with respect to materials and energy use. Although the green synthesis of nanoparticles is recently developed, many physical and chemical methods with many demerits are still being utilized. Hence, it is feasible to select appropriate method/s considering energy, cost, and environmental toxicity. Therefore, this review paper is intended to evaluate the physical, chemical and biological methods of nanoparticle synthesis considering the pros and cons of each method. The review also presents an overview of the historical development of Nanotechnology to show the time line advancement of this technology. This can help future researchers to make informed decisions when employing the various methods of nanoparticle synthesis.
Keywords: Nanotechnology, Nanoparticle synthesis methods, Green Chemistry, Bottom-up approach, Top-down Approach